Lipid Peroxides Profile (TBARS) - Serum

Lipid peroxides are the products of chemical damage done by oxygen free radicals to the polyunsaturated fatty acids of cell membranes. This test is an assay of total thiobarbituric acid-reactive substances (TBARS) in serum using HPLC. The HPLC separation step isolates the TBARS from potential interfering compounds that can give false elevations in a simple colorimetric assay. The results provide a measure of total serum lipid peroxidation, an indicator of whole body free radical activity. High levels of lipid peroxides are associated with cancer, heart disease, stroke, and aging.