Lipid Peroxides Profile - Serum

Lipid peroxides are the products of chemical damage done by oxygen free radicals to the polyunsaturated fatty acids of cell membranes. This test is an assay of total thiobarbituric acid-reactive substances (TBARS) in serum using HPLC. The HPLC separation step isolates the TBARS from potential interfering compounds that can give false elevations in a simple colorimetric assay. The results provide a measure of total serum lipid peroxidation, an indicator of whole body free radical activity. High levels of lipid peroxides are associated with cancer, heart disease, stroke, and aging.

Test name(s)

0051 - Lipid Peroxides

Description

Lipid peroxides are the products of chemical damage done by oxygen free radicals to the polyunsaturated fatty acids of cell membranes. This test is an assay of total thiobarbituric acid-reactive substances (TBARS) in serum using HPLC. The HPLC separation step isolates the TBARS from potential interferring compounds that can give false elevations in a simple colorimetric assay. The results provide a measure of total serum lipid peroxidation, an indicator of whole body free radical activity. High levels of lipid peroxides are associated with cancer, heart disease, stroke, and aging.

Method

HPLC

Turnaround time

6-8 days, 7 days average

Analytes

Lipid peroxides

Specimen Collection Instructions

• Fat-Soluble-Vitamins-KI.pdf

Sample Reports Example of how test results will be reported, including reference ranges and graphs indicating high and low percentiles of each analyte.

• Lipid-Peroxides-SR.pdf

Patient Briefs

• Oxidative-Stress-PB.pdf

If you do not have the free Adobe Acrobat Reader, download it here.

Articles

• Reactive Species and Antioxidant Markers - Normal cellular processes, ultraviolet rays from the sun, environmental pollutants and toxins, excessive intake of protein, total calories or alcohol, and even increased exercise, can increase reactive oxygen (ROS) and reactive nitrogen (RNS) species.

Books

• Laboratory Evaluations for Integrative and Functional Medicine - Your evidence-based resource for the biochemical basis of chronic illness. A must-have desk reference for laboratory testing associated with nutritional and metabolic medicine.

Presentations

• IFM: The New Paradigm of Medicine - This PowerPoint presentation was developed by the Institute for Functional Medicine. It provides a concise explanation of the new paradigm of medicine that focuses on underlying causes of disease and treatment from that level rather treating symptoms alone, the approach often taken by modern medicine.

References

• Lipid Peroxides (TBARS) References