The Russian scientist Elie Metchnikoff (1845 - 1916) popularized the idea of "Dys-symbiosis" or "Dysbiosis," describing an imbalance in the microecology of the digestive tract. When the microbial balance of the gut is disturbed, opportunistic, or "bad", bacteria can overgrow and mitigate the effects of the "good", predominant bacteria needed for a healthy gut.
The Organix Dysbiosis Profile is a urine organic acid test measuring the by-products of microbial metabolism, and is particularly useful in detecting the presence of pathogenic microbial overgrowth. As a stand-alone test, the Organix Dysbiosis Profile is a great follow-up option to the Organix Comprehensive Profile, allowing the clinician to assess microbial overgrowth and guide and monitor targeted therapy in patients.
Urine contains unique products of microbial metabolism which are used to measure small bowel yeast and bacterial overgrowth. With the exception of hippurate, the compounds measured in the Organix Dysbiosis Profile, such as D-arabinitol, are not normally produced by human cells. Unfriendly intestinal microorganisms, however, can manufacture them in relatively high quantities. These compounds are absorbed into the blood from the intestines and eventually appear in a urine organic acid test.
Stool testing also gives insight into the gut microbial population of the large bowel. Read more about the innovative GI Effects Stool Profile here.
The Organix Dysbiosis Profile and the GI Effects Stool Profile can be utilized together to gain an overall snapshot of a patient's gut health.