Reactive Species and Antioxidant Markers
- Normal cellular processes, ultraviolet rays from the sun, environmental pollutants and toxins, excessive intake of protein, total calories or alcohol, and even increased exercise, can increase reactive oxygen (ROS) and reactive nitrogen (RNS) species.
- If you’ve already had a heart attack, having elevated fibrinogen shows you who is most likely to die within less than four years. So if you have already had a heart attack and you’re not having your fibrinogen measured, you are being cheated because it is totally reversible.
The Fatty Acid Profile: Dietary Intake and Beyond
- Fatty acid testing can provide a great deal of information allowing for individualized interventions. Varying patterns can help to
identify not only essential fatty acid deficiency or excess, but also signs of insulin resistance, hypertriglyceridemia, proinflammation,
or omega-3 dominance.
Vitamin D: A Clinical Perspective
- Although its primary role is to regulate calcium and phosphorus absorption/resorption to maintain bone health, the clinical
significance of vitamin D is very broad. This article explains why vitamin D is so important to the body.
Why Test for Coenzyme Q10?
- This article illustrates that measuring both direct and indirect biomarkers of CoQ10 sufficiency in order to appropriately diagnose and treat patients, and to monitor CoQ10 administration, can markedly improve patient outcomes and prevent mitochondrial related disease.
Significance of Low Plasma Homocysteine
- Low plasma homocysteine is clinically relevant because multiple organ and system disturbances can result from limitation of sulfur compounds and methionine methyl donor functions.
Autistic Therapies Focused by Laboratory Data
- This review focuses on laboratory evaluation of organic acidurias for revealing metabolic weaknesses in autism that may be responsive to aggressive nutritional, detoxification and gastrointestinal immune balancing interventions.
Urinary Markers of Intestinal Yeast
- Letter to the editor of Towsend Letter for Doctors and Patients gives the argument against the use of urinary arabinose for detection of invasive candidiasis and for the use of urinary D-arabinitol instead.
Mineral Testing and Osteoporosis
- This is a case study involving a postmenopausal woman with osteoporosis. The case illustrates how whole blood minerals and toxic metals testing can give clues to causes of osteoporosis and help with supplement recommendations.
- Profound elevation of 5-HIA suggests a bowel-specific serotonin syndrome that is producing a hypersensitivity to changes in the bacterial colonies of the gut.
Fungal Overgrowth but not Invasive Candidiasis
- This case involved a 46-year-old female who was overweight and had poor muscle tone. She presented originally with chronic, severe headaches They improved with pressure and with the use of prednisone. This issue began at age 25.
- Evidence of profound mitochondrial oxidation lesions are seen in this infant with breathing difficulties.
Dysbiosis from Corticosteroid Use
- The common assumption that prolonged courses of corticosteroid treatment can precipitate Candida yeast infections have never been so evident as in this case.
- Extreme elevation of D-arabinitol presents an potential explanation of otherwise unexplained and unusual chronic symptoms.
Fat Malabsorption in Health Optimization
- When plasma fatty acid levels fail to respond to supplementation with oils rich in essential fatty acids, fat malabsorption is indicated, even when the symptoms of essential fatty acid deficiency are not yet reported.
- Mitochondrial distress with oxidative stress and extreme glutathione up-regulation is exacerbated by glycine conjugation insufficiency and intestinal bacterial overgrowth.
- A series of Organix reports shows the nature of this genetic abnormality as numerous, severe, and persistent metabolic disturbances.
- When follow up testing looks much worse while a young leukemia patient is improving, multiple factors are at play. Underlying dysbiosis and glutathione issues are involved in this case.
D-Lactate Study Set
- Seven cases illustrate a variety of other bacterial marker abnormalities when D-lactate is high. The patterns instruct about etiologies and intervention strategies.
High Amino Developmental Delay
- A combination of environmental, nutritional, and genetic metabolic weaknesses were found as potential causative factors in the failure of neurological development for this 2-year-old girl. Vitamin B6 insufficiency, arsenic exposure, and intestinal dysbiosis are key features in the initial laboratory workup.
Fishing Trip Heart Attack
- After his first heart attack, this man had delilgently followed all recommendations from standard cardiology. The low fat diet and regular exercise routines, lowered his body weight and blood lipids. Then he headed out for his annual fishing trip and another MI hit him. The Cardio ION revealed multiple additional cardiac risk factors needing correction.
Nutritional Solutions for High Blood Pressure
- In this second part of a three part series, Dr. Rogers explains why commonly prescribed medications for high blood pressure don’t always work and can sometimes make things worse.
How Cholesterol-Lowering Drugs Harm Nutrition
- We welcome Dr. Sherry Rogers, author of The Cholesterol Hoax, to this episode of the Metametrix Institute Podcast. Dr. Rogers says that cholesterol is not in fact, the biggest cause of heart disease, nor is it predictive of heart disease.
Why Test for Amino Acids?
- The Amino Acid Plasma 20 test is reviewed by Dr. Redmond. Each category is explained and the reasons for highs and lows are discussed.
Modifiable Risk Factors for Cardiovascular Disease
- Lipoprotein factors, inflammation markers, insulin, hormone markers, RBC magnesium and oxidative stress are discussed as the main features of the Cardiovascular Risk Profile. Recommendations are given to increase HDL, lower LDL, and reduce inflammation. Treatment options are given to reduce oxidative stress.
IFM: The New Paradigm of Medicine
- This PowerPoint presentation was developed by the Institute for Functional Medicine. It provides a concise explanation of the new paradigm of medicine that focuses on underlying causes of disease and treatment from that level rather treating symptoms alone, the approach often taken by modern medicine.
Evaluating the Complex Patient with Organix Testing
- Four cases are presented in this teleconference: an autistic child, a child with mitochondrial myopathy, an adult with depression and a professional athlete. Aspects of their organic acid tests are focused on.