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Detoxification Capacity - Saliva & Urine
Overview Clinician Info CPT Codes Kit Instructions Sample Reports Interpretive Guide References

Three compounds, caffeine, acetaminophen, and acetylsalicylic acid, are taken orally to challenge the liver's Phase I and Phase II detoxification capacity. Saliva and urine are analyzed for metabolites of the three compounds to determine how well the liver can convert and clear toxins from the body. This test is not recommended for children 12 years old and younger.

*Profile is not available in New York

Clinician Info
Test name: 0180* - Detoxification Capacity Profile
*Not available in New York
Description: Three compounds, caffeine, acetaminophen, and acetylsalicylic acid, are taken orally to challenge the liver’s Phase I and Phase II detoxification capacity. Saliva and urine are analyzed for metabolites of the three compounds to determine how well the liver can convert and clear toxins from the body. This test is NOT recommended for children 12 years old and younger.
Method: HPLC, Spectrophotometry
Turnaround time: 14-21 days, 14 days average
Analytes: Caffeine Clearance
o-Hydroxyhippuric Acid
Acetaminophen Sulfate
Acetaminophen Glucuronide
Phase I/ Phase II Ratios
Urine Lipid Peroxides
CPT codes:

82492 - Acetaminophen Glucuronide
82492 - Acetaminophen Sulfate
80101 - Caffeine Clearance
82570 - Creatinine
84311 - o-Hydroxyhippuric Acid
82491 - Urine Lipid Peroxides
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