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IgG4 Food Antibodies - Bloodspot 30

Next Generation in Food Sensitivity Testing

Breakthroughs in IgG Antibody Testing!

  • New patent pending IgG4 assay
  • First test to quantitate IgG4
  • Eliminate non-specific binding therefore eliminate false positives without rejecting true positives!

Allergix™ Bloodspot IgG4 Food Antibodies*

IgG antibodies are associated with non-atopic or "delayed" food reactions that can worsen or contribute to many different health problems. Food sensitivities can occur at any age, triggering many different symptoms and contribute to a variety of disorders.

From a simple finger stick, the Allergix™ Bloodspot™ IgG Food Antibody Profile measures levels of IgG antibodies specific to 30 commonly offending foods. It clearly identifies those foods that may be causing health problems, helping to achieve positive outcomes sooner, even when combined with elimination/provocation testing.

Food sensitivities can occur at any age, triggering many different symptoms and contributing to a variety of disorders, including:
  • Inflammatory bowel disease
  • Fatigue
  • ADD/ADHD
  • Migraines
  • Skin problems
  • Rheumatoid arthritis
  • Sinusitis
  • Recurrent ear infections

*Bloodspot profile not available in New York

Why Bloodspot™?:

  • Easy to implement in any practice
  • Does not require venipuncture
  • Cost-effective testing & therapy
  • Easy enough that patients can even do it at home
  • Simple and economical option for follow-up testing
Clinician Info
Test name: 0076* - IgG4 Food Antibodies - Bloodspot 30
Description: The Bloodspotâ„¢ IgG Food Antibody Assay is a blood spot test that measures the total IgG levels that react to common food antigens. The test kit is simple enough for the patient to use at home.
Method: ELISA
Turnaround time: 7-14 days, 10 days average
Antigens: Almond
Aspergillus Mold
Beef
Cantaloupe
Cashew
Chicken
Corn
Crab
Egg, Whole
Garlic
Lobster
Milk
Mustard Greens
Oat
Orange
Peanut
Pea, Green
Pinto Bean
Pork
Rice
Salmon
Shrimp
Soybean
Strawberry
Sunflower
Tomato
Tuna
Turkey
Walnut, English
Wheat

* This test is not available in New York
CPT codes:

86001 x 30 - Allergen Specific IgG quantitative or semiquantitative each allergen
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Food Antibodies References
 

Immunologic and clinical responses to parenteral immunotherapy in peanut anaphylaxis--a study using IgE and IgG4 immunoblot monitoring.
Bullock, R.J., D. Barnett, and M.E. Howden, Allergol Immunopathol (Madr), 2005. 33(5):250-6.

Food-specific IgG4 antibody-guided exclusion diet improves symptoms and rectal compliance in irritable bowel syndrome.
Zar, S., et al., Scand J Gastroenterol, 2005. 40(7): p. 800-7.

IgA rheumatoid factor and IgG dietary protein antibodies are associated in rheumatoid arthritis.
O'Farrelly, C., et al., Immunol Invest, 1989. 18(6): p. 753-64.

The gut-joint axis: cross reactive food antibodies in rheumatoid arthritis.
Hvatum, M., et al., Gut, 2006. 55(9): p. 1240-7.

The clinical significance of food specific IgE/IgG4 in food specific atopic dermatitis.
Noh G, Ahn HS, Cho NY, Lee S, Oh JW. Pediatr Allergy Immunol. 2007 Feb;18(1):63-70.

Food sensitivity case report
Betty Wedman-St Louis Original Internist,  Sept, 2006

Treating irritable bowel syndrome with a food elimination diet followed by food challenge and probiotics.
Drisko J, Bischoff B, Hall M, McCallum R. J Am Coll Nutr. 2006 Dec;25(6):514-22.

Treatment of delayed food allergy based on specific immunoglobulin G RAST testing.
Dixon, H. Otolaryngol Head Neck Surg 2000;123:48-54

Breaking the rules.
Aalbers RC, Schuurman, J. IgG Immunology, 2002, 105 9-19.

A subclass IgG4 specific antigen binding radioimmunoassay (RIA): comparison of IgG and IgG4
antibodies of food and inhaled antigens in adult atopic dermatitis after desensitization treatment and during development of antibody responses in children.

Rowntree, S., Platts-Mills, T.A, Cogeswell, MB. J ALLERGY CLIN IMMUNOL 1981;80:622-30.

Non-IgE antibody mediated mechanisms in food allergy
.
Halpern, G.M., Scott, J.R. Annals of Allergy, Vol 58, January 1987.

Assessing adherence to a rotary diversified diet, a treatment for 'environmental illness.
Taylor JP, Krondl MM, Csima AC. J Am Diet Assoc. 1998 Dec;98(12):1439-44.