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IGF-1 - Serum
Overview Clinician Info CPT Codes Kit Instructions Sample Reports Interpretive Guide References

Insulin-Like-Growth Factor Type 1

The Insulin-Like Growth Factor Type 1 (IGF-1) test measures serum levels of IGF-1 (also called Somatomedin C), an anabolic hormone produced in the liver and essential for maintenance of muscle tissue. Serum levels of IGF-1 vary depending on age, sex, growth hormone secretion, liver function, and nutritional status. Levels below normal are associated with chronic stress and fibromyalgia.

Clinician Info
Test name: 0045- Insulin-Like Growth Factor Type 1
Description: The Insulin-like Growth Factor Type I (IGF-1) test measures serum levels of IGF-1 (also called Somatomedin C), an anabolic hormone produced in the liver and essential for maintenance of muscle tissue. Serum levels of IGF-1 vary depending on age, sex, growth hormone secretion, liver function, and nutritional status. Levels below normal are associated with chronic stress and fibromyalgia.
Method: Chemiluminescence
Turnaround time: 6-9 days, 7 days average
Analytes: Somatomedin (IGF-1)
CPT codes:

84305 - Somatomedin
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IgF-1 References
  

Total serum insulin-like growth factor-1 and C-reactive protein in metabolic syndrome with or without diabetes.
Efstratiadis G, Tsiaousis G, Athyros VG, Karagianni D, Pavlitou-Tsiontsi A, Giannakou-Darda A, Manes C. Angiology. 2006 May-Jun;57(3):303-11.

Secretion of growth hormone in patients with chronic fatigue syndrome.
Berwaerts J, Moorkens G, Abs R. Growth Horm IGF Res. 1998 Apr;8 Suppl B:127-9.

Is further evaluation for growth hormone (GH) deficiency necessary in fibromyalgia patients with low serum insulin-like growth factor (IGF)-I levels?
Yuen KC, Bennett RM, Hryciw CA, Cook MB, Rhoads SA, Cook DM. Growth Horm IGF Res. 2007 Feb;17(1):82-8. Epub 2007 Feb 6.

The role of insulin-like growth factor I components in the regulation of vitamin D.
Gómez JM. Curr Pharm Biotechnol. 2006 Apr;7(2):125-32.

Serum insulin-like growth factor-I level is associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes mellitus.
Kanazawa I, Yamaguchi T, Yamamoto M, Yamauchi M, Yano S, Sugimoto T. Osteoporos Int. 2007 Jul 14.

Evaluation of Bone Loss and Its Mechanisms in Anorexia Nervosa.
Legroux-Gérot I, Vignau J, D'Herbomez M, Collier F, Marchandise X, Duquesnoy B, Cortet B. Calcif Tissue Int. 2007 Aug 1.

Serum concentration of insulin, C-peptide and insulin-like growth factor I in patients with colon adenomas and colorectal cancer.
Kaczka A, Kumor A, Pietruczuk M, Małecka-Panas E. Pol Merkur Lekarski. 2007 May;22(131):373-5.

Association between serum IgF-1 levels and thyroid disorders in a population-based study.
Völzke H, Friedrich N, Schipf S, Haring R, Lüdemann J, Nauck M, Dörr M, Brabant G, Wallaschofski H. J Clin Endocrinol Metab. 2007 Jul 31.

Insulin-like growth factor-1 as an indicator of nutrition during treatment of adolescent girls with eating disorders.
Swenne I, Stridsberg M, Thurfjell B, Rosling A. Acta Paediatr. 2007 Aug;96(8):1203-8.

Serum insulin-like growth factor-I levels among women in Hawaii and Japan with different levels of tofu intake.
Takata Y, Maskarinec G, Rinaldi S, Kaaks R, Nagata C. Nutr Cancer. 2006;56(2):136-42.

Tomato lycopene extract supplementation decreases insulin-like growth factor-I levels in colon cancer patients.
Walfisch S, Walfisch Y, Kirilov E, Linde N, Mnitentag H, Agbaria R, Sharoni Y, Levy J. Eur J Cancer Prev. 2007 Aug;16(4):298-303.

Relationship of dietary protein and soy isoflavones to serum IGF-1 and IGF binding proteins in the Prostate Cancer Lifestyle Trial.
Dewell A, Weidner G, Sumner MD, Barnard RJ, Marlin RO, Daubenmier JJ, Chi C, Carroll PR, Ornish D. Nutr Cancer. 2007;58(1):35-42.